Current Issue : October - December Volume : 2016 Issue Number : 4 Articles : 5 Articles
Background: Seungma-Galgeun-Tang (SMGGT), a traditional herbal medicinal formula, has been used to treat\nvarious skin problems such as inflammation and rashes in Korean traditional medicine. In order to clarify the\nscientific evidence for the biological efficacy of SMGGT on the prevention of skin aging and in particular wrinkle\nformation, molecular anti-wrinkle parameters were evaluated in cultured human dermal fibroblasts.\nMethods: Standard SMGGT was prepared from KFDA-certified herbal medicines and the chemical fingerprint of\nSMGGT was verified by HPLC-ESI-MS to insure the quality of SMGGT. To evaluate the inhibitory effects of SMGGT on\nthe synthesis of matrix metalloproteinase-1 (MMP-1) and type-1 procollagen, the content of MMP-1 and type-1\nprocollagen synthesizing enzymes in cultured human dermal fibroblasts were measured using an ELISA kit and\nWestern Blot, respectively.\nResults: The treatment of SMGGT water extract significantly inhibited the production of MMP-1 and promoted\ntype-1 procollagen synthesis concentration dependently.\nConclusions: These results suggest that SMGGT has the potential to prevent wrinkle formation by down-regulating\nMMP-1 and up-regulating type-1 procollagen in human dermal fibroblasts....
Many strong and extreme sensitizing chemicals, such as para-phenylenediamine (PPD),\ntoluene-2,5-diamine (TDA) and other aromatic amines or cross-reacting substances, are ingredients\nin hair dye products. The chemistry of hair dyeing and the immunological reactions to the potent\nsensitizing hair dye components are complex and have not been fully clarified up until now. Recently\n2-methoxymethyl-p-phenylenediamine (ME-PPD), a PPD derivate with moderate skin-sensitizing\nproperties, was developed. Although developed for the prevention of sensitization, ME-PPD appears\nto be tolerated in some PPD/TDA-allergic individuals....
Mushrooms have been valued as a traditional source of natural bioactive compounds\nfor centuries and have recently been exploited for potential components in the cosmetics industry.\nNumerous mushrooms and their ingredients have been known to be beneficial to the skin and\nhair. The representative ingredients are as follows: phenolics, polyphenolics, terpenoids, selenium,\npolysaccharides, vitamins, and volatile organic compounds. These compounds show excellent\nantioxidant, anti-aging, anti-wrinkle, skin whitening, and moisturizing effects, which make them\nideal candidates for cosmetics products. This review provides some perspectives of mushrooms\n(and/or extracts) and their ingredients presently used, or patented to be used, in both cosmeceuticals\nfor topical administration and nutricosmetics for oral administration. With the small percentage of\nmushrooms presently identified and utilized, more mushroom species will be discovered, verified,\nand cultivated in the future, boosting the development of relevant industry. Combining with progress\nin genomics, proteomics, metabolomics, and systems pharmacology, mushrooms can find their way\ninto cosmetics with multiple approaches....
Depigmentation and skin lightening products, which have been in use for ages in\nAsian countries where skin whiteness is a major esthetic criterion, are now also highly valued\nby Western populations, who expose themselves excessively to the sun and develop skin spots as\na consequence. After discussing the various possible mechanisms of depigmentation, the different\nmolecules that can be used as well as the status of the products containing them will now be\npresented. Hydroquinone and derivatives thereof, retinoids, alpha- and beta-hydroxy acids, ascorbic\nacid, divalent ion chelators, kojic acid, azelaic acid, as well as diverse herbal extracts are described in\nterms of their efficacy and safety. Since a genuine effect (without toxic effects) is difficult to obtain,\nprevention by using sunscreen products is always preferable....
A high peak power IPL system (Lumecca) was tested to determine the correlation between a high\npeak power and the successful treatment of pigmented and vascular lesions. Short pulse duration\nin the millisecond range and high peak power of 3.3 kW/cm2 enabled selective and effective destruction,\nnot only of pigment, but also of vessels in a comparable manner to a pulsed dye laser.\nOnly one treatment session at a low fluence (8 - 16 J/cm2) was sufficient to achieve the desired results....
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